Endocrine Abstracts

Introduction: Metachronic metastasis of renal carcinoma to the thyroid gland, a rare entity occurring sometimes many years after nephrectomy, have been already reported by literature. Thyroidal synchronous metastasis, instead, are more uncommon. We herein report a patient with thyroidal metastasis and intrajugular thrombo embolic involvement as initial presentation of a misunderstood renal carcinoma.Case Report: A 83-years-old woman, with silent medical ...

Biochemical control of acromegaly is currently defined by the achievement of GH suppression after oral glucose tolerance test (OGTT) and of normal age- and gender-matched IGF1 levels. OGTT is believed to inhibit somatotropin secretion by enhancing central somatostatinergic tone; thus, the use of this test in evaluating biochemical control in acromegalic patients on somatostatin analogues (SSA) is questionable. To gain further insights into this topic, we analyzed basal and nad...

Introduction: While searching for mechanisms contributing to the increased mortality of acromegaly, we have previously described an unexpected sympathoinhibition in newly diagnosed patients (Seravalle et al., Clin Endocrinol 77:262, 2012) and interpreted this finding as an adaptive phenomenon. It has also been shown that centrally administered somatostatin (SS) inhibits peripheral sympathetic outflow in rodents (Rettig et al., Am J Physiol 257:R588, 1989). Ba...